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DECLARE - Clinical Trial Spotlight
Stephen Wiviott, MD: Changes in the Treatment of Type 2 Diabetes
Wiviott, senior investigator of the DECLARE-TIMI 58 trial, says that SGLT2 inhibitors and GLP-1 receptor agonists are changing the paradigm of how clinicians manage diabetes and cardiovascular risk.
Stephen Wiviott, MD: Strengths and Limitations of the DECLARE-TIMI 58 Trial
Strengths of the DECLARE-TIMI 58 trial included a large primary prevention population, while the nature of the study meant that adherence was likely higher than it would be in a standard setting.
Dapagliflozin Reduces Heart Failure in Primary Prevention Population
The study showed noninferiority with relation to major adverse cardiovascular events and a reduction of heart failure, though no difference in cardiovascular death compared to placebo. There appear to be renal benefits to dapagliflozin as well.
Why Is Myasthenia Gravis So Difficult to Diagnose?
Deepak Bhatt, MD: Fighting Cardiovascular Disease
New Uterine Fibroids Oral Treatment Could Replace Surgery (UPDATE)
Interoperability Is the Key to a Patient-centric Transformation of the Healthcare System
John M. Kane, MD: The Benefits & Shortcomings of Schizophrenia Therapy
Affordable Care Act
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