Research using mouse models demonstrated that a high-fat diet increased intestinal permeability, which led to increases in circulating and local inflammatory cytokines, and increased choroidal neovascularization.
Treatment with recombinant adeno-associated virus vector gene-therapy was shown to be safe and potentially effective in a small test group of patients with neovascular age-related macular degeneration.
A new study out of Ireland examined the prevalence of extra-articular manifestations in axial spondyloarthritis, and found that women were at significantly higher risk for inflammatory bowel disease and uveitis than men.
The prevalence of noninfectious uveitis was 121 cases per 100,000 adults and 29 cases per 100,000 children. By such estimates, nearly 300,000 adults and 22,000 children in the United States had the disease in 2015.
Even when a 32-gauge needle was used, intravitreal injection posed a risk of introducing contamination directly into the eye. However, of all the needle gauges studied, the 27-gauge needle posed the greatest risk.