The MD Magazine Uveitis condition center provides clinical news and articles, information about upcoming conferences and meetings, updated clinical trial listings, and other resources.


PCR Testing Revolutionized Diagnosis, Treatment of Infectious Uveitis
A 12-tube polymerase chain reaction strip can detect 24 ocular pathogens.
Annual rate of ocular inflammatory flares fell from 200 to 49 per 100 patients.
The FDA’s decision follows the EU’s decision last month to similarly expand the scope of the drug’s approval to include more specific causes of vision loss and blindness.
Monitoring Zika-exposed patients for visual symptoms and ocular findings is particularly important because these may be the only indicators of the infection in some patients.
Some cases of tubulointerstitial nephritis and uveitis syndrome, or TINU, have a poor visual prognosis, so early diagnosis and treatment are recommended. Diagnosis requires detailed history taking, whole-body imaging studies, and examination of renal function.
In the SAKURA study, a greater proportion of those in the intravitreal sirolimus treatment groups than those in the active control group met the primary endpoint, a vitreous haze score of zero at Month 5 without the use of rescue therapy.
A retrospective review of patients with bilateral uveitic glaucoma who had filtration surgery in both eyes at different times found that the second surgically treated eye showed greater glaucomatous disc progression than the first.
A Spanish research team found an association between testing positive for antibodies to adalimumab (Humira) and a worse outcome of uveitis, but only in those who tested positive permanently. They also found that this association correlated with undetectable trough levels of Humira.
Most patients with severe refractory juvenile ideiopathic arthritis-associated uveitis may get complete remission after six months of treatment with tocilizumab (Actemra/Roche.)

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